AP Biology · Unit 5 · Topic 5.4
Non-Mendelian Genetics
Meiosis, chromosome behavior, and probability models connect inheritance patterns to genetic variation.
1. Topic Lens
Non-Mendelian Genetics is studied through heredity. Connect the system boundary, interacting parts, and measurable evidence before applying a formula.
2. Why the Formula Works
The relationship is built from definitions and conservation reasoning:
- List the outcomes and decide whether the events are independent.
- For independent events, the fraction satisfying both is the product of the individual fractions.
- Use addition instead when mutually exclusive routes can produce the same outcome.
3. Detailed Visual Model
4. Worked Example and Lab Link
Two independently inherited traits each show a 3/4 dominant-phenotype probability. What is the probability of both?
Answer: The probability is (3/4)(3/4)=9/16.
Investigation idea: Use cards or beads as alleles to simulate many crosses, then compare observed and expected ratios.
Common trap: Multiply only independent probabilities; linkage, epistasis, and small samples can disrupt simple ratios.
Explain how non-mendelian genetics supports or limits this conclusion: The probability is (3/4)(3/4)=9/16.
Official curriculum reference: College Board AP Biology course page. The explanation and worked example are independently written for this study site.