AP Course

AP Biology

Updated for the AP Biology framework effective fall 2025, with concept lessons, data reasoning, quizzes, and practice problems.

Explore life from molecules and cells to evolution and ecosystems through the official AP Biology unit sequence.

AP Biology · Unit 5 · Topic 5.4

Non-Mendelian Genetics

Meiosis, chromosome behavior, and probability models connect inheritance patterns to genetic variation.

1. Topic Lens

Non-Mendelian Genetics is studied through heredity. Connect the system boundary, interacting parts, and measurable evidence before applying a formula.

\[P(A\cap B)=P(A)P(B)\]

2. Why the Formula Works

The relationship is built from definitions and conservation reasoning:

  1. List the outcomes and decide whether the events are independent.
  2. For independent events, the fraction satisfying both is the product of the individual fractions.
  3. Use addition instead when mutually exclusive routes can produce the same outcome.
\[P(\text{both independent events})=\prod_i P_i\]

3. Detailed Visual Model

Pixel diagram for Non-Mendelian GeneticsOriginal schematic connecting Non-Mendelian Genetics to Heredity.
Non-Mendelian Genetics: an original pixel-style model. Use it as a schematic, not a literal scale drawing.

4. Worked Example and Lab Link

Two independently inherited traits each show a 3/4 dominant-phenotype probability. What is the probability of both?

Answer: The probability is (3/4)(3/4)=9/16.

Investigation idea: Use cards or beads as alleles to simulate many crosses, then compare observed and expected ratios.

Common trap: Multiply only independent probabilities; linkage, epistasis, and small samples can disrupt simple ratios.

Checkpoint · Topic 5.4

Explain how non-mendelian genetics supports or limits this conclusion: The probability is (3/4)(3/4)=9/16.

Official curriculum reference: College Board AP Biology course page. The explanation and worked example are independently written for this study site.